An immune complex, sometimes called an antigen-antibody complex, is a molecule formed from the integral binding of an antibody to a soluble antigen. The bound antigen and antibody act as a unitary object, effectively an antigen of its own with a specific epitope. Type III hypersensitivity occurs when there is accumulation of immune complexes (antigen-antibody complexes) that have not been adequately cleared by innate immune cells, giving rise to an inflammatory response and attraction of leukocytes. Such reactions may progress to immune complex diseases. Immune complexes may themselves cause illness when they are deposited in organs, for example, in certain forms of vasculitis.
For More: http://www.sciaeon.org/immunology-and-infections/home
Manuscript Submission: http://www.sciaeon.org/immunology-and-infections/submit-paper
Contact: immunology@sciaeonopenaccess.com
Immunology & Infection 